basic FUNCTION
| regulating selectively the apical recycling and/or transcytotic pathway |
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involved in apical vesicle trafficking |
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increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress |
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RAB11A, and RAB25 promote cell migration by regulating vesicular transport and recycling of surface receptors |
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acts predominantly in the small-scale fast recycling within the tips of the cell |
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controls intestinal cell polarity through the regulation of gene expression |
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can promote bladder metastasis through induction of epithelial-mesenchymal transition process and activation of AKT1/GSK3B/SNAI1 signaling pathway |
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epithelial-specific, and heavily implicated in ovarian cancer development, it independently appears to act as a tumour suppressor in the context of a distinct subset of carcinomas |