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FLASH GENE

Symbol

PWRN1

contributors: mct - updated : 17-03-2020

HGNC name	Prader-Willi region non-protein-coding RNA 1
HGNC id	33235

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	15q11.2      Physical location : 24.803.303 - 24.832.924
Synonym name	non-protein coding RNA 198
Synonym symbol(s)	NCRNA00198, FLJ25418

DNA

TYPE

small rna

regulatory sequence

Binding site

MAPPING

cloned

Y

linked

N

status

provisional

Map	cen - NIPA1 - NIPA2 - TUBGCP5 - MKRN3 - MAGEL2 - NDN - PWRN2 - PWRN1 - C15orf2 - SNURF /SNRPN - IPW - UBE3A - ATP10A - GABRB3 - GABRA5 - GABRG3 - qter
Authors	Buiting (07)

RNA

TRANSCRIPTS	type	untranslated small nuclear

EXPRESSION

Rna function	low expression in Gastric cancer (GC)tissues and cells
	suppressed GC development via TP53 signaling pathway
	located in microdeletion of PWS, covering a region from MKRN3, MAGEL2, NDN, PWRN2, PWRN1, C12orf2, SNURF-SNRPN, C/D snoRNAs
Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis       Urinary kidney

cells

System Cell Pubmed Species Stage Rna symbol Reproductive spermatozoa

cell lineage	expressed in post-meiotic germ cells only
cell lines
fluid/secretion

at STAGE

IMPRINTING
text	bi-allelically expressed in testis and kidney, but mono-allelically in fetal brain

PROTEIN

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS