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FLASH GENE
Symbol PURG contributors: - updated : 05-07-2005
HGNC name purine-rich element binding protein G
HGNC id 17930
Location 8p11      Physical location : 30.853.320 - 30.891.231
Synonym name
  • Pur-gamma
  • Synonym symbol(s) PURG-A, PURG-B
    DNA
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
    text
  • lies in close proximity to the Werner syndrome gene, but on the opposite strand
  • 10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Binding site   transcription factor
    text structure
  • positively regulated by Sp1 elements
  • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1972 39 347 - Liu
  • transcription through the variant 2 polyadenylation site and splicing out of an intron of >30 kb
  • - splicing 2709 36 322 - Liu
  • single intronless transcript
  • differing in the 3' UTR and coding region compared to variant A
  • EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   moderately
    Reproductivefemale systemovary  moderately
     male systemprostate  moderately
    Respiratorylung   lowly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine Purg
    intraspecies homolog to purine-rich element binding protein A
    Homologene
    FAMILY
  • Pur protein family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS