basic FUNCTION
| tyrosine phosphatase, functioning as an oncogene in prostate cancer |
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promotes cell migration and invasion through an ERK-dependent signaling pathway |
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implicated in the control of cell proliferation and invasion |
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is required for extra-embryonic development |
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is likely required for spermatogenesis during testis development |
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PTP4A1, PTP4A2, PTP4A3 are key contributors to metastasis in several human cancers |
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pivotal role for PTP4A2 2 in regulating cellular magnesium homeostasis |
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oncogenic PTP4A2 controls tumor growth by modulating intracellular magnesium levels through binding with the CNNM3 magnesium transporter |
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plays critical roles in regulating hematopoietic stem cell (HSC) self-renewal and mediating stem cell factor (SCF)/KIT signaling |
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is involved in cell-type-specific Mg(2+) homeostasis and its expression is potentially inversely regulated by dietary Mg(2+) levels |