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FLASH GENE
Symbol PTMS contributors: - updated : 02-03-2006
HGNC name parathymosin
HGNC id 9629
Location 12p13.32      Physical location : 6.875.540 - 6.880.116
Synonym name formerly assigned to 17q12-q22
Synonym symbol(s) THYP
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
LOC390284 12 similar to signal recognition particle 14kDa (homologous Alu RNA binding protein); signal recognition particle 14kD (homologous Alu RNA-binding protein); signal recognition particle 14kD (homologous Alu RNA binding protein) TNFRSF7 12p13 tumor necrosis factor receptor superfamily, member 7 TAPBP-R 12p13.31 TAP binding protein related VAMP1 12p13.31-p13.2 vesicle-associated membrane protein 1 (synaptobrevin 1) PKP2P1 12p13 vesicle-associated membrane protein 1 (synaptobrevin 1) MRPL51 12p13.3-p13.1 mitochondrial ribosomal protein L51 CNAP1 12p13.3 chromosome condensation-related SMC-associated protein 1 GAPD 12p13.31 glyceraldehyde-3-phosphate dehydrogenase HOM-TES-103 12p13.3 HOM-TES-103 tumor antigen-like NOL1 12p13.31 nucleolar protein 1, 120kDa CHD4 12p13 chromodomain helicase DNA binding protein 4 GPR92 12p13.32 G protein-coupled receptor 92 ACRBP 12p13.32 acrosin binding protein ING4 12p13.32 inhibitor of growth family, member 4 ZNF384 12p12 zinc finger protein 384 DKFZp547D2210 12p13.31 hypothetical protein DKFZp547D2210 COPS7A 12p13.32 COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) MLF2 12p13 myeloid leukemia factor 2 PTMS 12p13.32 parathymosin LAG3 12p13.32 lymphocyte-activation gene 3 CD4 12p13.31 CD4 antigen (p55) GRCA 12p13 likely ortholog of mouse gene rich cluster, A gene LEPREL2 12q13 leprecan-like 2 protein USP5 12p13 ubiquitin specific protease 5 (isopeptidase T) GNB3 12p13.31 guanine nucleotide binding protein (G protein), beta polypeptide 3 CDCA3 12p13 cell division cycle associated 3 TPI1 12p13.31 triosephosphate isomerase 1 GRCC9 12p13.31 likely ortholog of mouse gene rich cluster, C9 gene B7 12p13 B7 gene ENO2 12p13.31 enolase 2, (gamma, neuronal) DRPLA 12p13.31 dentatorubral-pallidoluysian atrophy (atrophin-1) GRCC10 12p13.31 likely ortholog of mouse gene rich cluster, C10 gene PTPN6 12p13.31 protein tyrosine phosphatase, non-receptor type 6 REA 12p13.31 protein tyrosine phosphatase, non-receptor type 6 C2F 12p13 C2f protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   moderately
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivefemale systemuterus  highly
Urinarykidney    
Visualeye   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to prothymosin,highly
Homologene
FAMILY
CATEGORY signaling hormone
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • may be mediating immune function by blocking the effect of prothymosin alpha, which confers resistance to certain opportunistic infections
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS