Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PTGFR contributors: - updated : 14-09-2005
HGNC name prostaglandin F receptor (FP)
HGNC id 9600
Location 1p31.1      Physical location : 78.956.727 - 79.006.385
Synonym name
  • PGF receptor
  • PGF2 alpha receptor
  • prostaglandin F2 alpha receptor
  • prostanoid FP receptor
    • Synonym symbol(s) FP, PF2R
    DNA
    TYPE functioning gene
    STRUCTURE 47.00 kb     3 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 2565 - 297 heart and placenta, skeletal muscle Vielhauer
    71 bp insert producing a frame shift resulting in a truncated receptor lacking transmembrane-7 and the intracellular carboxyl tail
    - splicing 3466 - 359 - Vielhauer
    - splicing - - - - Vielhauer
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemprostate   
    Visualeyeanterior segmentiris  
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connective    
    Epithelial    
    Muscularsmooth   
    Muscularsmouthciliary  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		seven transmembrane segments (7TM)
    HOMOLOGY
    interspecies homolog to murine Ptgfr
    Homologene
    FAMILY G protein coupled receptor superfamily
    CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • potent luteolytic agent, may be involved in modulating intraocular pressure and smooth muscle contraction in uterus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   LOH    
    in breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS