protein
| binds a PEST-type protein tyrosine phosphatase |
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associates directly or indirectly with actin |
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acts as a negative feedback regulator of CSF1R signaling to suppress inflammation and osteoclastogenesis  |
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assembly of FNBP1 on the plasma membranes is antagonized by PSTPIP2, another F-BAR protein implicated in auto-inflammatory disorder  |
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inhibits actin polymerization by competing with FNBP1 for assembly at artificial as well as the plasma membrane  |
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is a negative regulator of CASP1-autonomous IL1B production  |
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assembly of FNBP1 is dependent on WAS, and its dissociation by WAS inhibition strongly induces a self-organization of PSTPIP2 at podosomes  |
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is a GATA1-repressed gene that controls megakaryopoiesis  |
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PSTPIP2 interacted with LYN and the expression of a dominant negative LYN (LYN DN) overwhelmed the inhibitory effect of PSTPIP2 on differentiation and ERK signaling  |