Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PSORS1C1 contributors: mct - updated : 21-06-2012
HGNC name psoriasis susceptibility 1 candidate 1
HGNC id 17202
Corresponding disease
PSORS1 familial psoriasis 1
Location 6p21.3      Physical location : 2.378.425 - 31.107.867
Synonym name
  • SEEK1 protein
  • chromosome 6 open reading frame 16
    • Synonym symbol(s) SEEK1, C6orf16, MGC132530
    DNA
    TYPE functioning gene
    SPECIAL FEATURE
    text telomeric to the HLA-C locus
    STRUCTURE 25.22 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 913 16.45 152 - 2003 12930300
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Nervousbrainhindbrainmedulla oblongata  
    Reproductivefemale systemovary   
     female systemuterus   
     female systembreastmammary gland  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PSORS1
    Susceptibility
  • to psoriasis
  • to systemic sclerosis
    • Variant & Polymorphism SNP , other
  • +39604 polymorphism in chromosome 6p associated with psoriasis
  • rs3130573 increasing the risk of systemic sclerosis
    • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS