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FLASH GENE
Symbol PSMD13 contributors: - updated : 10-02-2007
HGNC name proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
HGNC id 9558
Location 11p15.5      Physical location : 236.807 - 252.984
Synonym name hypothetical protein 26S proteasome subunit p40.5
Synonym symbol(s) P40.5, HSPC027 , PSDD
DNA
TYPE functioning gene
SPECIAL FEATURE head to head
text with SIRT3
STRUCTURE 15.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC390028 11 similar to Olfactory receptor 4F3 LOC387731 11 similar to bA476I15.3 (novel protein similar to septin) LOC387732 11 LOC387732 RYD5 11p15.5 ligand binding protein RYD5 ODF3 11p15.5 outer dense fiber of sperm tails 3 BET1L 11p15.5 blocked early in transport 1 homolog (S. cerevisiae) like RIC-8 11p15.5 likely ortholog of mouse synembryn SIRT3 11p15.5 sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) PSMD13 11p15.5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 NALP6 11p15 NACHT, leucine rich repeat and PYD containing 6 FLJ22635 11p15.5 hypothetical protein FLJ22635 LOC387733 11 similar to putative haemopoietic membrane protein MRPS24P1 11p15.4 mitochondrial ribosomal protein S24 pseudogene IFITM2 11p15.5 interferon induced transmembrane protein 2 (1-8D) IFITM1 11p15.5 interferon induced transmembrane protein 1 (9-27) IFITM3 11p15.5 interferon induced transmembrane protein 3 (1-8U) PKP3 11p15 plakophilin 3 LOC387734 11 similar to beta 1,4-N-acetylgalactosaminyltransferase-transferase-III FLJ25045 11p15.5 hypothetical protein FLJ25045 SIGIRR 11p15.5 single Ig IL-1R-related molecule PTDSS2 11p15 phosphatidylserine synthase 2 RNH 11p15.5 ribonuclease/angiogenin inhibitor LOC387735 11 similar to Collagen alpha 1(V) chain precursor HRAS 11p15.5 v-Ha-ras Harvey rat sarcoma viral oncogene homolog DKFZp761L1518 11p15.5 hypothetical protein DKFZp761L1518 MGC35138 11p15.5 hypothetical protein MGC35138 C11orf13 11p15,5 chromosome 11 open reading frame 13 KIAA1542 11p15.5 CTD-binding SR-like protein rA9 IRF7 11p15,5 interferon regulatory factor 7 MUCDHL 11p15,5 mucin and cadherin-like SCT 11p15.5 secretin DRD4 11p15.5 dopamine receptor D4 LOC387736 11 LOC387736 DEAF1 11p15,5 deformed epidermal autoregulatory factor 1 (Drosophila) LOC283232 11p15.5 hypothetical protein LOC283232 EPS8L2 11p15.5 EPS8-like 2 TALDO1 11p15.5-p15.4 transaldolase 1 FLJ34283 11p15.5 hypothetical protein FLJ34283 NS3BP 11p15.5 NS3BP BM88 11p15.5 NS3BP SLC25A22 11p15.5 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 LOC387737 11 LOC387737 LRDD 11pter-p15.5 leucine-rich and death domain containing
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1587 - 377 - Hoffman
- - 1672 - 351 - Hoffman
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineadrenal gland   highly
Reproductivefemale systemovary  highly
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one PCI domain
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION acting as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component component of the PA700 complex
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS