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FLASH GENE
Symbol PSMB1 contributors: - updated : 25-02-2004
HGNC name proteasome (prosome, macropain) subunit, beta type, 1
HGNC id 9537
Location 6q27      Physical location : 170.844.204 - 170.862.417
Synonym name proteasomal subunit C5
Synonym symbol(s) PMSB1,PSB1,HC5
EC.number 3.4.25.1
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 18.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
cytosine-phosphate-guanine/HTF
text structure a methylation free CpG island spanning their promoter region
MAPPING cloned Y linked N status provisional
Physical map
MLLT4 6q27 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 LOC202546 6q27 hypothetical LOC202546 C6orf54 6q27 chromosome 6 open reading frame 54 KIF25 6q27 kinesin family member 25 FRMD1 6q27 FERM domain containing 1 LOC389450 6 LOC389450 LOC154323 6q27 hypothetical LOC154323 MGC33437 6q27 meningioma expressed antigen 6 (coiled-coil proline-rich) pseudogene DACT2 6q27 dapper homolog 2, antagonist of beta-catenin (xenopus) SMOC2 6q27 SPARC related modular calcium binding 2 LOC346055 6q27 similar to Hypothetical protein CBG10550 THBS2 6q27 thrombospondin 2 LOC391988 6 similar to SPCPB16A4.07c MGC43690 6q27 hypothetical protein MGC43690 PHF10 6q27 PHD finger protein 10 TCTE3 6q27 t-complex-associated-testis-expressed 3 C6orf208 6q27 chromosome 6 open reading frame 208 LOC154449 6q27 hypothetical protein LOC154449 DLL1 6q27 delta-like 1 (Drosophila) KIAA1838 6q27 KIAA1838 PSMB1 7p12 proteasome (prosome, macropain) subunit, beta type, 1 TBP 6q27 TATA box binding protein PDCD2 6q27 programmed cell death 2 LOC391989 6 similar to Olfactory receptor 4F3
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemprostate   
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer polymer
HOMOLOGY
interspecies homolog to murine Psmb1
Homologene
FAMILY PSM,proteasome B type family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION involved in an ATP/ubiquitin-dependent non-lysosomal proteolytic pathway
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component component 20 S (prosome-macropain) of multicatalytic proteinase complex of proteasome
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS