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FLASH GENE
Symbol PSG1 contributors: - updated : 03-01-2006
HGNC name pregnancy specific beta-1-glycoprotein 1
HGNC id 9514
Location 19q13.2      Physical location : 43.370.612 - 43.383.871
Synonym symbol(s) PSGGA, SP1, B1G1, PBG1, CD66f, PSBG1, DHFRP2, FLJ90598, FLJ90654, PSGIIA-a, PSGIIA-b, PSGIIA-c, PSG IIA-d
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 12.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text produced in high quantity during pregnancy, placenta specific, placental syncytiotrophoblasts
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three Ig-like C2-type (immunoglobulin-like) domains
  • a Ig-like V-type (immunoglobulin-like) domain
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY carcinoembryonic antigen (CEA family)
    k1 Ig immunoglobulin superfamily
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • contributing to immunomodulation during pregnancy, with opposite effects on maternal innate and adaptative systems
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS