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FLASH GENE
Symbol PSD4 contributors: mct - updated : 28-11-2016
HGNC name pleckstrin and Sec7 domain containing 4
HGNC id 19096
Location 2q13      Physical location : 113.931.559 - 113.960.676
Synonym name
  • telomeric of interleukin 1 cluster
  • ADP-ribosylation factor guanine nucleotide-exchange factor 6
  • PH and SEC7 domain-containing protein 4
  • Synonym symbol(s) EFA6B, TIC, FLJ36237, FLJ37279
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     16 Exon(s)    single Copie(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 5039 116 1056 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • SEC7 domain
  • PH domain
  • HOMOLOGY
    Homologene
    FAMILY
  • pleckstrin-like family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • maybe mediating protein-protein and protein-lipid interactions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • novel ARF6 activation mechanism by DNM2 through PSD4 and PSD3 in clathrin-mediated endocytosis (CME)in a manner dependent upon the GTPase activity of DNM2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS