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FLASH GENE
Symbol PRSS22 contributors: - updated : 22-12-2003
HGNC name protease, serine, 22
HGNC id 14368
Location 16p13.3      Physical location : 2.902.727 - 2.908.171
Synonym name
  • tryptase epsilon
  • brain-specific serine protease 4
  • protease, serine S1 family member 22
  • serine protease 26
  • Synonym symbol(s) BSSP-4, MGC9599, SP001LA, UNQ302/PRO343
    EC.number 3.4.21.-
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text part of a cluster of serine protease genes
    STRUCTURE 5.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    FLJ39075 16p13.3 hypothetical protein FLJ39075 KCTD5 16p13.3 potassium channel tetramerisation domain containing 5 MPN 16p13.3 pancreasin SRRM2 16p13.3 serine/arginine repetitive matrix 2 TCEB2 13q12.1 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) LOC246718 16p12.3 ranscription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) pseudogene EOS 16p13.3 serine protease EOS TESSP1  testis serine protease 1 PRSS21 16p13.3 protease, serine, 21 (testisin) LOC124220 16p13.3 similar to common salivary protein 1 MGC52282 16p13.3 hypothetical protein MGC52282 PRSS22 16p13.3 protease, serine, 22 LOC114984 16p13.3 hypothetical protein BC014089 DKFZp761A132 16p13.3 hypothetical protein DKFZp761A132 FLJ30002 16p13.3 hypothetical protein FLJ30002 KREMEN2 16p13.3 kringle containing transmembrane protein 2 PKMYT1 16p13.3 kringle containing transmembrane protein 2 LOC388205 16 similar to RIKEN cDNA 1520401A03 gene
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreas    
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cells
    SystemCellPubmedSpeciesStageRna symbol
    respiratorylarynx
    respiratorylung
    respiratorytrachea
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text lung highly
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a peptidase S1 domain
    HOMOLOGY
    interspecies homolog to Drosophila cg8170
    homolog to C.elegans c07g1.1
    Homologene
    FAMILY peptidase family S1
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be involved in proteolysis and peptidolysis
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other developmentally regulated (repressed by time)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS