Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PRPF3 | contributors: mct - updated : 23-01-2012 |
HGNC name | PRP3 pre-mRNA processing factor 3 homolog (yeast) |
HGNC id | 17348 |
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Corresponding disease |
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Location | 1q21.3 Physical location : 150.293.927 - 150.325.703 | ||
Synonym name | U4/U6-associated RNA splicing factor | ||
Synonym symbol(s) | HPRP3, HPRP3P, PRP3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 31.78 kb 16 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
| a PWI domain commonly present in splicing factors |
mono polymer | heteromer , complex |
HOMOLOGY |
interspecies | ortholog to yeast S.cerevisiae prp3 |
Homologene |
FAMILY |
CATEGORY | RNA associated |
CELLULAR PROCESS | nucleotide, RNA splicing |
protein, translation/synthesis |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/vision |
INTERACTION |
DNA |
RNA | binding to U4 and U6 snRNAs |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | spliceosomal PRPF19 complex modifies PRPF3, a component of the USP4, with nonproteolytic K63-linked ubiquitin chains |
ASSOCIATED DISORDERS |
corresponding disease(s) | RP18 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |