protein
| heat shock protein 60, Hsp60 ![](pubmed.jpg) |
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casein kinase 2, CK2 ![](pubmed.jpg) |
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plasminogen ![](pubmed.jpg) |
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neuronal phosphoprotein synapsin Ib, Grb2, and Pint1 ![](pubmed.jpg) |
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stress-inducible protein 1, STI1 ![](pubmed.jpg) |
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heparin ![](pubmed.jpg) |
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tubulin ![](pubmed.jpg) |
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heterogeneous nuclear ribonucleoprotein A2/B1 and aldolase C ![](pubmed.jpg) |
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lipoprotein receptor-related protein 1, LRP1 ![](pubmed.jpg) |
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clusterin ![](pubmed.jpg) |
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Abeta42 oligomers ![](pubmed.jpg) |
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ADAM23 ![](pubmed.jpg) |
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STIP1 (PMID : ![](pubmed.jpg) |
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kinesin and dynein ![](pubmed.jpg) |
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Hsp70 ![](pubmed.jpg) |
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thiamine ![](pubmed.jpg) |
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KCTD1 is a molecular interaction partners of the cellular prion protein (PRNP) ![](pubmed.jpg) |
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ADAM8 can perform alpha-cleavage of PRNP and PRNP can regulate ADAM8 expression ![](pubmed.jpg) |
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amyloid-beta precursor protein ![](pubmed.jpg) |
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FOXO3 negatively regulates PRNP expression by binding to the PRNP promoter, which is negatively regulated by insulin-like growth factor 1 (IGF1) ![](pubmed.jpg) |
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interacts with BECN1 to recruit the PIK3C3 complex into lipid rafts and thus activates autophagy in response to Abeta42, defining a novel role of PRNP in the regulation of autophagy ![](pubmed.jpg) |
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AMFR is critical for unglycosylated PRNP ubiquitylation and degradation ![](pubmed.jpg) |
| mice expressing DeltaPrP or Dpl suffer from widespread leukoencephalopathy ![](pubmed.jpg) | |
mouse expressing the PrP(DeltaCD), a PrP variant lacking 40 central residues, displays a rapidly progressive, lethal phenotype with extensive central and peripheral myelin degeneration ![](pubmed.jpg) |
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ablation of the prion protein PrP(C) triggers a chronic demyelinating polyneuropathy in four independently targeted mouse strains ![](pubmed.jpg) |
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absence of PrPC in a transgenic Alzheimer mouse rescues deficits in spatial learning and memory ![](pubmed.jpg) |
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Knockdown PRNP homolog in the zebrafish leads to a dose-dependent phenotype characterized by systemic morphological defects, reduced cell adhesion and CNS cell death ![](pubmed.jpg) |