| basic FUNCTION
| cytosolic serine-threonine kinase binding to the trans-Golgi network and regulating the fission of transport carriers specifically destined to the cell surface |
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inducing pre-T cell proliferation |
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implicated in the regulation of cell shape, adhesion, and migration |
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playing a role in actin remodelling |
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having a negative regulatory function in cell migration |
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regulates the dynamics of actin turnover through phosphorylation of proteins of the actin polymerization machinery, such as cortactin |
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key regulator of the cofilin signaling pathway thereby controlling actin remodeling and polarized cell motility in cervix carcinoma, breast cancer, and pancreatic cancer cells |
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role in contraction-induced SLC2A4 translocation and the combined actions of PRKD1 on TNNI3 phosphorylation and on SLC2A4 translocation would efficiently link accelerated contraction mechanics to increased energy production when the heart is forced to increase its contractile activity  |
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highly effective class II HDAC kinase, and key regulator of skeletal muscle function |
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plays a role in numerous processes including cell proliferation, cell survival, immune cell signaling, gene expression, vesicle trafficking, and neuronal development |
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role in cardiomyocyte signal transduction through effects on class IIa HDACs |
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upstream regulator of cortactin (CTTN) and function in actin organization as well as cell migration |
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potentially important role in controlling cancer progression and metastasis |
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PRKD1-mediated phosphorylation of DLC1 on serine 807 negatively regulates DLC1 cellular function |
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key signaling enzyme that mediate a range of physiologically important cellular responses |
