| basic FUNCTION
| serine/threonine kinase, critically involved in the regulation of differentiation and proliferation of T lymphocytes |
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its activation induces insulin-mediated vasoconstriction by inhibition of Akt and stimulation of ERK1/2 in muscle resistance arteries |
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PRKCQ-dependent oxidative signaling organelles involved in activation-induced T-cell death |
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cooperates with atypical PRKCZ and PRKCI in NF-kappaB transactivation of T lymphocytes  |
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PRKCA and PRKCQ have overlapping functions in alloimmunoreactivity and both PRKCQ and PRKCA isotypes must be targeted to prevent organ allograft rejection |
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in regulatory T cells, inhibits their function and, intriguingly, is sequestered from the activating cellular interface |
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maintains the correct structure and function of the heart by preventing cardiomyocyte cell death in response to work demand and to neuro-hormonal signals |
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serine/threonine kinase that plays an essential role in antigen-regulated responses of T lymphocytes |
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implicated in several physiological processes regulating the activation response of platelets |
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involved in the regulation of hemostasis and thrombosis |
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critical TCR signaling molecule that promotes the activation and differentiation of naive T cells into inflammatory effector T cells |
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able to control T cell-mediated immune responses by shifting the balance between the differentiation of effector T cells and inhibitory Tregs |
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integrates the signals from TCR signaling and Th17 priming cytokines to upregulate STAT3 via NFKB and AP1, resulting in the stimulation of Th17 differentiation |
