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FLASH GENE
Symbol PRH1 contributors: - updated : 10-05-2006
HGNC name proline-rich protein HaeIII subfamily 1
HGNC id 9366
Location 12p13.2      Physical location : 11.033.559 - 11.324.210
Synonym name
  • parotid acidic protein
  • Parotid double-band protein
  • Synonym symbol(s) Pa
    DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked Y status provisional
    Map see PR@
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver   moderately
     salivary gland   highly
    Nervousbrain   moderately
    Respiratoryrespiratory tractlarynx  highly
     respiratory tracttrachea  highly
    Urinarykidney   highly
    Visualeye   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion salivary
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES acid
    STRUCTURE
    motifs/domains proline-rich protein
    HOMOLOGY
    interspecies ortholog to murine Prp/Prh1
    homolog to C.elegans Y67D8C.E
    Homologene
    FAMILY Hae III subfamily 1
    CATEGORY secretory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • acting as highly potent inhibitors of crystal growth of calcium phosphates
  • providing a protective and reparative environment for dental enamel which is important for the integrity of the teeth
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS