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FLASH GENE
Symbol PRG3 contributors: mct/npt - updated : 17-03-2010
HGNC name proteoglycan 3
HGNC id 9363
Location 11q12.1      Physical location : 57.144.242 - 57.148.623
Synonym name
  • eosinophil major basic protein homolog
  • prepro-major basic protein homolog
    • Synonym symbol(s) MBPH, MBP2, MGC126662, MGC141971, Prepro-MBPH
    DNA
    TYPE functioning gene
    STRUCTURE 4.38 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 886 - 225 - Plager (2001)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Connectivebone   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • lectin C type domain
    • mono polymer heteromer
    HOMOLOGY
    intraspecies homolog to PRG5
    Homologene
    FAMILY
  • plasticity-related gene family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in immune response
  • brain-specific integral membrane protein implicated in neuronal plasticity, such as filopodia formation and axon growth after brain lesion (Broggini 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS