Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PRELID3A contributors: mct - updated : 05-07-2016
HGNC name PRELI domain containing 3A
HGNC id 24639
Location 18p11.21      Physical location : -
Synonym name
  • erythroid differentiation and denucleation factor 1
  • protein slowmo homolog 1
  • slowmo homolog 1
  • Synonym symbol(s) C18orf43, HFL-EDDG1, SLMO1
    DNA
    TYPE functioning gene
    STRUCTURE 24.34 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1734 - 172 - 2015 26071602
    7 - 1731 - 172 - 2015 26071602
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a PRELI domain chaperoned during import into the intermembrane mitochondrial space
  • a TRIAP1-binding region delineated by the region between residues P13 and L39, which encompasses the edge beta2 strand, an ordered proline-rich loop and the alpha1-helix
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,interspace
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • likely regulate the subsequent biosynthesis of phosphatidylethanolamine (PE) or phosphatidylcholine (PC)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • PRELID3A with its mitochondrial chaperones (TRIAP1) represent a unique heterodimeric lipid transfer system that is evolutionary conserved from yeast to man
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS