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FLASH GENE
Symbol PRDM4 contributors: - updated : 22-03-2004
HGNC name PR domain containing 4
HGNC id 9348
Location 12q23-q24.1      Physical location : 108.126.643 - 108.154.914
Genatlas name positive regulatory domain family protein 4
Synonym name
  • PR family member 1
  • PR-domain zinc-finger protein PFM1
  • Synonym symbol(s) MGC45046,PFM1
    DNA
    TYPE functioning gene
    STRUCTURE 27.00 kb     11 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivefemale systemovary   
     male systemtestis   
     male systemprostate   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one SET domain
  • six zinc finger DNA binding motifs, C2H2 type at the C terminus
  • HOMOLOGY
    Homologene
    FAMILY PR-domain protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in cell differentiation control and in tumorigenesis
  • CELLULAR PROCESS cell cycle
    nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS