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FLASH GENE
Symbol PRDM15 contributors: - updated : 27-02-2007
HGNC name PR domain containing 15
HGNC id 13999
Location 21q22.3      Physical location : 43.218.386 - 43.299.591
Genatlas name positive regulatory domain family protein 15
Synonym name
  • putative gene containing C2 domain
  • zinc finger protein 298
  • chromosome 21 open reading frame 83
    • Synonym symbol(s) ZNF298, C21orf83, PFM15
    DNA
    TYPE functioning gene
    STRUCTURE 81.00 kb     20 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 6687 - 1178 - Shibuya
    - - 6747 - 1198 - Shibuya
    - - 6695 - 555 - Shibuya
    - - 6575 - 515 - Shibuya
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     tonsils   moderately
    Reproductivefemale systemovary  moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a SET [Su(var)3-9, Enhancer-of-zeste, Trithorax] domain
  • multiple C2H2-type zinc finger (ZnF_C2H2) domains
  • several nuclear localization signals (NLSs)
  • and PEST sequences
    • HOMOLOGY
    Homologene
    FAMILY PR-domain protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    ZN2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS