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FLASH GENE
Symbol PPP4R1 contributors: npt/ - updated : 15-09-2005
HGNC name protein phosphatase 4, regulatory subunit 1
HGNC id 9320
Location 18p11.22      Physical location : 9.546.791 - 9.614.600
Synonym name serine/threonine phosphatase 4
Synonym symbol(s) PP4R1, MEG1, PP4(Rmeg)
DNA
TYPE functioning gene
STRUCTURE 67.81 kb     20 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LAMA1 18p11.32-p11.22 laminin, alpha 1 LOC390828 18 similar to mitochondrial carrier triple repeat 1 LOC339291 18p11.23 similar to RIKEN cDNA 2610040E16 PTPRM 18p11.2 protein tyrosine phosphatase, receptor type, M FLJ11996 18p11.22 hypothetical protein FLJ11996 LOC125831 18p11.22 similar to constitutive photomorphogenic protein LOC390829 18 similar to Aldose reductase (AR) (Aldehyde reductase) LOC201475 18p11.22 similar to Rab12 protein KIAA0802 18p11.21 similar to Rab12 protein LOC390830 18 similar to ribosomal protein S4, X-linked NDUFV2 18p11.22-p11.21 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa KIAA0874 TWSG1 18p11.3-p11.2 twisted gastrulation homolog 1 (Drosophila) RALBP1 18p11.3 ralA binding protein 1 PPP4R1 18p11.22 protein phosphatase 4, regulatory subunit 1 LOC125242 18p11.22 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) RAB31 18p11.31-p11.22 RAB31, member RAS oncogene family TXNDC2 18p11.31-p11.2 thioredoxin domain containing 2 (spermatozoa) VAPA 18p11.21 VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa APCDD1 18p11.21 adenomatosis polyposis coli down-regulated 1 NAPG 18p11.21 N-ethylmaleimide-sensitive factor attachment protein, gamma LOC390831 18 similar to Phosphomannomutase 2 (PMM 2) FLJ23403 18p11.21 hypothetical protein FLJ23403 LOC342843 18p11.21 similar to hypothetical protein LOC284221 18p11.21 hypothetical protein LOC284221 FLJ34907 18p11.21 hypothetical protein FLJ34907 LOC388463 18 similar to acyl-malonyl condensing enzyme LOC388464 18 hypothetical gene supported by D86974 GNAL 18p11.31 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type CHMP1.5 18p11.21 CHMP1.5 protein MPPE1 18p11.21-p11.1 CHMP1.5 protein IMPA2 18p11.22-p11.21 inositol(myo)-1(or 4)-monophosphatase 2 LOC284226 18p11.21 similar to Kinesin-like protein KIF1C LOC284227 18p11.21 similar to single stranded DNA binding protein 4 LOC162835 18p11.21 similar to G protein-coupled receptor 124 LOC342850 18p11.21 similar to KIAA1074 protein
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3976 106.9 950 - -
- - 3925 105.1 933 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • thirteen heat repeats
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to murine Ppp4r1
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • PPP4 complex contains at least a catalytic and a regulatory subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PPP4C
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS