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FLASH GENE
Symbol PPP2R3B contributors: - updated : 17-05-2005
HGNC name protein phosphatase 2 (formerly 2A),regulatory subunit B'',beta
HGNC id 13417
Location Xp22.33      Physical location : 244.668 - 347.690
Synonym symbol(s) PPP2R3L, PPP2R3LY, NY-REN-8
EC.number 3.1.3.16
DNA
TYPE functioning gene
STRUCTURE 52.00 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
regionally located located in the pseudoautosomal region 1 (PAR1)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1244 - 176 - Hendrix, Gao
- - 2071 - 575 - Hendrix, Gao
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousnervecranial nerve  highly
Reproductivefemale systemuteruscervix highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY protein phosphatase regulatory subunit family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • may be involved in the cell cycle-specific dephosphorylation of the Src substrate Cas (p130 Crk-associated substrate)
  • modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic
  • enzyme to a particular subcellular compartment
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS