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FLASH GENE
Symbol PPM1N contributors: mct - updated : 25-11-2020
HGNC name protein phosphatase, Mg2+/Mn2+ dependent 1N
HGNC id 26845
Location 19q13.32      Physical location : 46.001.730 - 46.005.762
Synonym symbol(s) FLJ40125
EC.number 3.1.3.16
DNA
TYPE
STRUCTURE 4.73 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1751 - 430 - 2004 14702039
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • conserved catalytic core region, which contains the metal-chelating residues
    • HOMOLOGY
    Homologene
    FAMILY metal-dependent protein phosphatase (PPM) family
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • involved in regulating diverse cellular functions, such as cell cycle control, cell differentiation, immune responses, and cell metabolism
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Ser/Thr phosphatases that bind manganese/magnesium ions (Mn2+/Mg2+) in their active center and function as single subunit enzymes
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene for CTRCT35
    Marker
    Therapy target
    ANIMAL & CELL MODELS