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FLASH GENE
Symbol PPIL4 contributors: npt/ - updated : 18-11-2003
HGNC name peptidylprolyl isomerase (cyclophilin)-like 4
HGNC id 15702
Location 6q25.1      Physical location : 149.825.630 - 149.867.171
Synonym name
  • rotamase
  • serologically defined breast cancer antigen NY-BR-18
  • cyclophilin-type peptidyl-prolyl cis-trans isomerase
  • Synonym symbol(s) HDCME13P, PPIase
    EC.number 5.2.1.8
    DNA
    TYPE functioning gene
    STRUCTURE 41.54 kb     13 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    SASH1 6q24.3 similar to iodotyrosine dehalogenase protein LOC340151 6q24.3 similar to laminin receptor 1 (ribosomal protein SA); P40-3, functional; P40-8, functional; laminin receptor 1 (67kD, ribosomal protein SA) UST 6q24.3-q25.1 uronyl-2-sulfotransferase MAP3K7IP2 6q25.1-q25.3 mitogen-activated protein kinase kinase kinase 7 interacting protein 2 LOC340152 6q24.3 similar to hypothetical protein D730019B10 PPIL4 6q24-q25 peptidylprolyl isomerase (cyclophilin)-like 4 C6orf72 6q24.3 chromosome 6 open reading frame 72 LOC389433 6 LOC389433 KATNA1 6q25.1 katanin p60 (ATPase-containing) subunit A 1 LATS1 6q24-q25.1 LATS, large tumor suppressor, homolog 1 (Drosophila) NUP43 6q24.3 nucleoporin 43kDa PCMT1 6q22.3-q24 protein-L-isoaspartate (D-aspartate) O-methyltransferase LRP11 6q24.3 low density lipoprotein receptor-related protein 11 RAET1E 6q25 retinoic acid early transcript 1E ULBP2 6q25 UL16 binding protein 2 ULBP1 6q25 UL16 binding protein 1 LOC345829 6q24.3 similar to Transcription factor BTF3 (RNA polymerase B transcription factor 3) LOC391980 6 similar to UL16 binding protein 1; alcan-beta RAET1L 6q25 retinoic acid early transcript 1L PHBP1 6q25 prohibitin pseudogene 1 ULBP3 6q25 UL16 binding protein 3 PPP1R14C 6q24.3-q25.3 protein phosphatase 1, regulatory (inhibitor) subunit 14C RNU4P1 6q25.1 RNA, U4 small nuclear pseudogene 1 (U4/7) LOC389434 6 similar to iodotyrosine dehalogenase protein PLEKHG1 6q25.1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 FTHFSDC1 6q25.1 formyltetrahydrofolate synthetase domain containing 1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 - 2481 57.1 492 - Zeng (2001)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Urinarykidney   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text brain
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • PPiase motif (peptidyl prolyl cis-trans isomerase)
  • RNA recognition motif (RRM)
  • bipartite nuclear targeting sequence (NLS)
  • lysine-rich domain
  • HOMOLOGY
    interspecies homolog to murine Ppil4
    Homologene
    FAMILY
  • cyclophilin-type PPIase family
  • PPIL4 subfamily
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • peptidylprolyl isomerase activity
  • CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA associated
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS