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FLASH GENE
Symbol PPIL3 contributors: npt/ - updated : 23-06-2006
HGNC name peptidylprolyl isomerase (cyclophilin)-like 3
HGNC id 9262
Location 2q33      Physical location : 201.735.679 - 201.753.849
Synonym name
  • cyclophilin J
  • rotamase
  • Synonym symbol(s) CyPJ, PPIase
    EC.number 5.2.1.8
    DNA
    TYPE functioning gene
    STRUCTURE 18.00 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text Variants PPIL3b and PPIL3c encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1191 18.5 165 - Zhou
    using alternative exon 4A
    - splicing 1179 18 161 heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary Zhou
    alternative exon 4B and a different 5'utr
    - - 1620 18 161 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen    
     thymus    
    Cardiovascularheart    
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivefemale systemovary   
     male systemtestis   
     male systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • CSA binding and peptidyl prolyl cis-trans isomerase (PPIase) sites flanked by variable N and C termini
  • HOMOLOGY
    Homologene
    FAMILY
  • immunophilin class M family
  • cyclophilin family
  • CATEGORY enzyme , receptor
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS