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FLASH GENE
Symbol PPFIBP2 contributors: - updated : 03-05-2002
HGNC name PTPRF interacting protein, binding protein 2 (liprin beta 2)
HGNC id 9250
Location 11p15.5      Physical location : 7.535.000 - 7.674.989
DNA
TYPE functioning gene
STRUCTURE 104.00 kb     23 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status provisional
Map pter - D11S1318 TH - MUC2 - CTSD - D11S1760 - RPL27A ,PPFIBP2 - LMO1 - D11S909 - cen
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3900 88 783 - Serra-Pages
- - 5100 - - heart, skeletal muscle Serra-Pages
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal coiled coil domain for dimerization and a C terminal LH (liprin homology) domain
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies ortholog to C.elegans celiprin beta 4
    intraspecies paralog to liprin beta 1
    Homologene
    FAMILY liprin family
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein alpha liprin PPFIA through the LH domain
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS