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FLASH GENE
Symbol POTEA contributors: mct/npt - updated : 20-08-2009
HGNC name POTE ankyrin domain family, member A
HGNC id 33893
Location 8p11.1      Physical location : 43.147.584 - 43.218.328
Synonym name
  • protein expressed in prostate, ovary, testis, and placenta 8
  • ANKRD26-like family A, member 1
  • Synonym symbol(s) POTE-8, POTE8, A26A1, CT104.3
    DNA
    TYPE functioning gene
    STRUCTURE 70.75 kb     14 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 splicing 1838 51.3 452 - Bera (2004)
  • differs from POTE8A in that it has only 4 ankyrin repeats
  • missing exon 5
  • 14 - 1976 56.2 498 - Bera (2004)
    having 5 ankyrin repeats
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemprostate  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N-terminal cysteine rich domain (CRD), palmitoylated on paired cysteine residues in each CRD motif (palmitoylation is responsible of the strong association with plasma membrane)
  • five ankyrin repeats
  • spectrin-like helices
  • HOMOLOGY
    intraspecies paralog to POTED
    Homologene
    FAMILY
  • POTE family
  • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    basic FUNCTION
  • having an important signaling function in the reproductive system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS