basic FUNCTION
| required for electron transfer from NADP to cytochrome p450 in microsomes |
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can also provide electron transfer to heme oxygenase and cytochrome B5 |
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electron donor for all microsomal P450 enzymes including CYP26A1 involved in inactivation of all-trans retinoic acid |
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flavoprotein that acts as the obligatory electron donor to all microsomal P450 enzymes, including those involved in hepatic drug metabolism as well as three steroidogenic P450 enzymes |
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microsomal electron-transferring enzyme, which provides the reducing equivalents to various redox partners, such as cytochromes P450 (CYPs), heme oxygenase (HO), cytochrome b(5) and squalene monooxygenase |
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involved in regulation of gap junction function and GJA1 may play an important role in POR-mediated bone defects seen in patients |
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plays a role in transcriptional regulation of GJA1 in osteoblasts and, as a consequence could be an important player in POR-mediated bone development |