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FLASH GENE
Symbol POP7 contributors: - updated : 08-07-2005
HGNC name processing of precursor 7, ribonuclease P subunit (S. cerevisiae)
HGNC id 19949
Location 7q22      Physical location : 100.303.675 - 100.305.122
Synonym symbol(s) RPP2, RPP20
EC.number 3.1.26.5
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon moderately
Lymphoid/Immunelymph node   moderately
Nervousbrain   moderately
Reproductivefemale systemovary  highly
 female systemplacenta  highly
Respiratoryrespiratory tractlarynx  predominantly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer complex
HOMOLOGY
interspecies ortholog to murine Pop7
Homologene
FAMILY small nucleolar ribonucleoprotein (snoRNP) particles
CATEGORY enzyme , RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleolus
basic FUNCTION
  • endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
  • generating mature tRNA molecules by cleaving their 5'ends
  • CELLULAR PROCESS nucleotide, transcription, maturation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic
    signaling
  • tRNA processing
  • a component
  • nucleolar ribonuclease P complex
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS