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FLASH GENE
Symbol POLR2J2 contributors: mct/npt - updated : 04/10/2008
HGNC name polymerase (RNA) II (DNA directed) polypeptide J2
HGNC id 23208
Location 7q22.1      Physical location : 102.277.471 - 102.312.182
Genatlas name DNA directed RNA polymerase II polypeptide J-related
Synonym name polymerase (RNA) II (DNA directed) polypeptide J, related gene
Synonym symbol(s) HRPB11B, RPB11b1, MGC54043, MGC105050
EC.number 2.7.7.6
DNA
TYPE functioning gene
STRUCTURE 34.70 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
FLJ14117 COL26A1 7q22.1 collagen, type XXVI, alpha 1 MYLC2PL 7q22.1 myosin light chain 2, precursor lymphocyte-specific CUTL1 7q22 cut-like 1, CCAAT displacement protein (Drosophila) APS 7q22 adaptor protein with pleckstrin homology and src homology 2 domains LOC392083 7 similar to Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3) LOC389542 7 similar to Williams-Beuren syndrome critical region protein 19 LOC389543 7 similar to postmeiotic segregation increased 2-like 9 LOC392084 7 similar to Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3) PRKRIP1 7q22.1 PRKR interacting protein 1 (IL11 inducible) C7orf19 7q22.1 chromosome 7 open reading frame 19 FLJ20013 7q22.1 hypothetical protein FLJ20013 DKFZp434K1815 7q22.1 hypothetical protein DKFZp434K1815 POLR2J 7q11.2 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa HSPC047 7q22.1 HSPC047 protein RASA4 7q22-q31.1 RAS p21 protein activator 4 POLR2J2 7q11.22 polymerase (RNA) II (DNA directed) polypeptide J, related gene MGC35361 7q22.1 hypothetical protein MGC35361 MGC21636 LRRC17 7q22 leucine rich repeat containing 17 SVH 7q22.1 SVH protein NAPE-PLD 7q22.1 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D LOC392085 7 similar to 60S ribosomal protein L23a FLJ36166 7q22.1 hypothetical protein FLJ36166 LOC392086 7 similar to Putative S100 calcium-binding protein A11 pseudogene LOC389544 7 similar to hypothetical protein FLJ32949 PMPCB 7q21.3-q22.1 peptidase (mitochondrial processing) beta ZRF1 7q22.1-q22.3 zuotin related factor 1 PSMC2 7q22.1-q22.3 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PRES 7q22.1 prestin (motor protein) RELN 7q22 reelin
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 590 13.3 117 - Fanciulli, Shpakovskii (2006)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Lymphoid/Immunethymus   highly
Nervousnerve   highly
Reproductivefemale systemuteruscervix highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • conserved 18AA region present in other RNA polymerase subunits
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to C.elegans w01g7.3
    Homologene
    FAMILY
  • eukaryotic RBP11/RPC119 RNA polymerase subunit family
  • RNA polymerase II subunit 11 gene family
  • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • encode a subunit of RNA polymerase II, the polymerase
  • responsible for synthesizing messenger RNA
  • DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SATB1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS