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FLASH GENE
Symbol POLDIP3 contributors: mct/npt - updated : 26-08-2008
HGNC name polymerase (DNA-directed), delta interacting protein 3
HGNC id 23782
Location 22q13.2      Physical location : 42.979.727 - 43.010.962
Synonym name
  • polymerase delta interacting protein 46
  • RNA-binding protein P46
  • S6K1 Aly/REF-like target
  • Synonym symbol(s) PDIP46, KIAA1649, SKAR, p46
    DNA
    TYPE functioning gene
    STRUCTURE 31.00 kb     9 Exon(s)
    regulatory sequence
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 3435 46 421 - Liu, Ma (2008)
    - - 3348 - 392 - Liu, Ma (2008)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouth   highly
    Lymphoid/Immunelymph node    
    Nervousbrain   highly
    Reproductivemale systemtestis  highly
    Respiratoryrespiratory tracttrachea  highly
    Skin/Tegumentskin    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text stem cells
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one RNA recognition motif (RRM)
  • HOMOLOGY
    interspecies homolog to rattus LOC315170
    homolog to murine Poldip3
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in the regulation of cell growth and its interaction with enhancer of rudimentary may suggest some function for enhancer of rudimentary in that control
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacting with RPS6KB1 and increasing the translation efficiency of spliced mRNA
  • target of RPS6KB1 which regulates cell growth
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS