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FLASH GENE
Symbol PNISR contributors: mct - updated : 26-01-2013
HGNC name PNN-interacting serine/arginine-rich protein
HGNC id 21222
Location 6q16.2      Physical location : -
Synonym name
  • serine-arginine-rich-splicing regulatory protein 130
  • splicing factor, arginine/serine-rich 130
    • Synonym symbol(s) HSPC261, C6orf111, HSPC306, RP11-98I9.2, SFRS18, SRrp130, bA98I9.2
    DNA
    TYPE functioning gene
    STRUCTURE 25.37 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 3142 - 805 - 2003 14578391
    11 - 3222 - 605 - 2003 14578391
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • multiple arginine-serine (RS) repeats but had no RNA recognition motif
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • three SR-rich proteins were identified that interact with the C-terminus of PNN: SRSF4 and SRRM2, known components of spliceosome machinery, and PNISR
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS