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FLASH GENE
Symbol PLLP contributors: mct - updated : 28-01-2014
HGNC name plasma membrane proteolipid (plasmolipin)
HGNC id 18553
Location 16q13      Physical location : 57.290.009 - 57.318.584
Synonym name
  • plasmolipin
  • transmembrane 4 superfamily member 11 (plasmolipin)
  • Synonym symbol(s) PMLP, TM4SF11
    DNA
    TYPE functioning gene
    STRUCTURE 28.57 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 1514 20 182 - 2001 1170778
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Endocrinepancreas    
    Nervousbraindiencephalonhypothalamus   Homo sapiens
    Reproductivemale systemprostate   
     male systemtestis   
    Urinarykidney     Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer trimer , hexamer
    HOMOLOGY
    interspecies homolog to murineTm4sf11
    intraspecies homolog to CMTM8
    Homologene
    FAMILY
  • MAL family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in myelination, and could also participate in ion transport events as addition of plasmolipin to lipid bilayers
  • functions as a voltage-dependent potassium ion channel and is expressed primarily in kidney and brain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS