protein
| targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase |
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target of PPARG, a key regulator of adipogenesis |
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physical interaction of LIPE with PLIN1 (can interact with an N-terminal region located between AAs 141 and 200 of PLIN1 as well as with a C-terminal region located between AAs 406 and 480) |
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ABHD5, a protein activator of PNPLA2, coordinates with PLIN1 in controlling basal and stimulated lipolysis |
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NR1H3 binds to the proximal regions of the PLIN1 and LIPE promoters |
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C-terminal 64 AAs of PLIN5 are critical for the differential binding of PNPLA2 to PLIN5 and PLIN1 |
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PLIN1, another adipocyte-specific lipid droplet-associated protein, is an CIDEC activator (interacts with the CIDE-N domain of CIDEC and markedly increases CIDEC-mediated lipid exchange, lipid transfer and lipid droplet growth) |