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FLASH GENE
Symbol PLD5 contributors: mct - updated : 16-03-2011
HGNC name phospholipase D family, member 5
HGNC id
Location 1q43      Physical location : 242.252.271 - 242.687.998
Synonym name
  • inactive choline phosphatase 5
  • inactive phosphatidylcholine-hydrolyzing phospholipase D5
  • inactive phospholipase D5
    • Synonym symbol(s) FLJ40773, MGC120565, MGC120566, MGC120567, PLDC
    DNA
    TYPE functioning gene
    STRUCTURE 435.70 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 2729 - 536 - 2009 19626040
    - - 2856 - 328 - 2009 19626040
    - - 3018 - 474 - 2009 19626040
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • its activity plays an important role in promoting IgE-dependent signaling events within lipid microdomains in mast cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorders
    Variant & Polymorphism SNP rs2196826 associated with autism spectrum disorders
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS