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FLASH GENE
Symbol PLCXD2 contributors: mct - updated : 07-09-2015
HGNC name phosphatidylinositol-specific phospholipase C, X domain containing 2
HGNC id
Location 3q13.2      Physical location : 111.393.522 - 111.565.294
DNA
TYPE
MAPPING cloned   linked   status
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 2148 - 305 - 2012 22732399
4 - 2053 - 304 - 2012 22732399
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart     Homo sapiens
Digestiveintestinelarge intestine    Homo sapiens
 intestinesmall intestine    Homo sapiens
Lymphoid/Immunethymus     Homo sapiens
Nervousbrain   predominantly Homo sapiens
Urinarykidney     Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatum    Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • only the X-domain of the normal X and Y catalytic domains found in all known mammalian PLC family members and are also devoid of all other regulatory domains
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • putative transcriptional role
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
  • may be an integral component of a nuclear phosphoinositide signalling pathway
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS