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FLASH GENE
Symbol PLCH1 contributors: np - updated : 22-11-2006
HGNC name phospholipase C, eta 1
HGNC id 29185
Location 3q25.31      Physical location : 155.197.670 - 155.421.997
Synonym name
  • phospholipase C-like 3
  • phospholipase C-eta1b
  • rat inositol 1-4-5 triphosphate binding protein homolog
  • Synonym symbol(s) KIAA1069, MGC117152, PLCL3, DKFZp434C1372, PLCeta1
    DNA
    TYPE functioning gene
    STRUCTURE 116.00 kb     21 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    21 - 6065 184 1655 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunethymus   highly
    Nervousbrainhindbraincerebellum lowly
     braindiencephalonamygdala lowly
    Reproductivefemale systemovary  lowly
     male systemtestis  lowly
    Respiratoryrespiratory tractlarynx  highly
    Urinarybladder   lowly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a C2 domain
  • an EF-hand domain
  • a PI-PLC X-box domain
  • a PI-PLC Y-box domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • phosphoinositide phospholipase C activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling signal transduction
  • intracellular signaling cascade
  • a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS