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FLASH GENE
Symbol PKD2L2 contributors: npt/ - updated : 13-10-2005
HGNC name polycystic kidney disease 2-like 2
HGNC id 9012
Location 5q31.2      Physical location : 137.225.124 - 137.276.156
Synonym name polycystin-like 2
DNA
TYPE functioning gene
STRUCTURE 51.03 kb     14 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - D5S396 - D5S479 - PKD2L2 - D5S414 - D5S500 - qter
Authors Veldhuisen (99)
Physical map
LOC391835 5 similar to Hypothetical protein FLJ20189 SPOCK 5q31 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) KLHL3 5q31 kelch-like 3 (Drosophila) HNRPA0 5q31 heterogeneous nuclear ribonucleoprotein A0 NPY6R 5q31 neuropeptide Y receptor Y6 (pseudogene) TTID 5q31 titin immunoglobulin domain protein (myotilin) PKD2L2 5q31 polycystic kidney disease 2-like 2 C5orf5 5q31 chromosome 5 open reading frame 5 WNT8A 5q31 wingless-type MMTV integration site family, member 8A NME5 5q31.1 non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) BRD8 5q31.2 bromodomain containing 8 KIF20A 5q31 kinesin family member 20A CDC23 5q31.1 CDC23 (cell division cycle 23, yeast, homolog) GFRA3 5q31.1-q31.3 GDNF family receptor alpha 3 CDC25C 5q31 cell division cycle 25C C5orf6 5q31 chromosome 5 open reading frame 6 C5orf7 5q31 chromosome 5 open reading frame 7 LOC51308 5q31 SGC32445 protein EGR1 5q31.1 early growth response 1 ETF1 5q31.1 eukaryotic translation termination factor 1 HSPA9B 5q31.1 heat shock 70kDa protein 9B (mortalin-2) LOC391836 5 similar to ribosomal protein L10a CTNNA1 5q31.1 catenin (cadherin-associated protein), alpha 1, 102kDa LRRTM2 5q31.3 catenin (cadherin-associated protein), alpha 1, 102kDa SIL1 5q31 endoplasmic reticulum chaperone SIL1, homolog of yeast
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 2236 72.36 613 - -
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • containing six (? to eight) transmembrane segments
  • cytoplasmic N and C termini
  • a cation transient receptor potential channel (TRPL) motif
  • a cation channel TM motif
  • a channel pore calcium-sodium motif
  • HOMOLOGY
    interspecies homolog to murine Pkd2l2
    Homologene
    FAMILY
  • polycystin family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    text integral membrane protein
    basic FUNCTION
  • maybe functioning as a subunit of a cation channel and playing a role in fertilization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • protein constituent of integral membrane
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS