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FLASH GENE
Symbol PIPSL contributors: mct - updated : 16-04-2014
HGNC name PIP5K1A and PSMD4-like
HGNC id 23733
Location 10q23.33      Physical location : 95.717.896 - 95.721.672
Synonym symbol(s) PSMD4P2, PIP5K1L1, PIP5K1P3, bA429H9.1
DNA
TYPE like-sequence
SPECIAL FEATURE
text fusion of phosphatidylinositol-4-phosphate 5-kinase (PIP5K1A) and 26S proteasome subunit (S5a/PSMD4) genes
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • tightly regulated, testis-specific novel ubiquitin-binding protein formed by an unusual exon-shuffling mechanism in hominoid primates and represents a key example of rapid evolution of a testis-specific gene
  • is an extraordinary co-retroposed protein-coding gene that may participate in the male functions of humans and its close relatives
  • has some function and is conserved among modern populations
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS