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FLASH GENE
Symbol PIN4 contributors: - updated : 18-05-2004
HGNC name protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
HGNC id 8992
Location Xq13      Physical location : 71.401.525 - 71.483.814
Synonym symbol(s) EPVH,PAR14
EC.number 5.2.1.8
DNA
TYPE functioning gene
STRUCTURE 11.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland    
 pancreas    
 thyroid    
Nervousbrainforebraincerebral lobefrontal lobe 
Reproductivemale systemprostate   
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal WW (phosphoserine-or phosphothreonine binding) domain
  • a unique C terminal peptidyl prolyl-isomerase domain
    • HOMOLOGY
    Homologene
    FAMILY PPIase family,parvulin subfamily
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION may be involved in ribosome biogenesis and/or nucleolar re-assembly of mammalian cells
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS