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FLASH GENE
Symbol PIGC contributors: - updated : 03-01-2005
HGNC name phosphatidylinositol glycan, class C
HGNC id 8960
Location 1q23-q25      Physical location : 172.410.597 - 172.413.230
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     1 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
LOC391133 1 similar to hypothetical protein BC015183 FMO3 1q23-q24 flavin containing monooxygenase 3 LOC388714 1 similar to Putative dimethylaniline monooxygenase [N-oxide forming] 6 (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6) FMO2 1q23-q25 flavin containing monooxygenase 2 FMO1 1q23-q25 flavin containing monooxygenase 1 PRO1257 1q24.1 hypothetical protein PRO1257 FMO4 1q23-q25 flavin containing monooxygenase 4 HCP3 1q23.3 cytochrome c, somatic pseudogene XTP2 1q23.3 HBxAg transactivated protein 2 MYOC 1q24.3-q25.2 myocilin, trabecular meshwork inducible glucocorticoid response LOC391134 1 similar to Chain  , Profilin LOC391135 1 similar to ribosomal protein L4; 60S ribosomal protein L4; homologue of Xenopus ribosomal protein L1 VAMP4 1q24-q25 vesicle-associated membrane protein 4 LOC391136 1 similar to RNA binding motif protein 3 CGI-01 1q24-q25.3 CGI-01 protein LOC391137 1 similar to dJ612B18.1 (similar to 40S ribosomal protein) LOC127099 1q24.1 similar to 60S ACIDIC RIBOSOMAL PROTEIN P1 KIAA0820 1q24 similar to 60S ACIDIC RIBOSOMAL PROTEIN P1 LOC92346 1q24.1 LOC92346 PIGC 1q23-q25 phosphatidylinositol glycan, class C C1orf9 1q24 chromosome 1 open reading frame 9 TNFSF6 1q23.3 tumor necrosis factor (ligand) superfamily, member 6 LOC391138 1 similar to Multisynthetase complex auxiliary component p43 TNFSF18 1q23 tumor necrosis factor (ligand) superfamily, member 18 LOC391139 1 similar to Aspartate aminotransferase, mitochondrial precursor (Transaminase A) (Glutamate oxaloacetate transaminase-2) TNFSF4 1q25 tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) LOC343153 1q24.2 similar to ribosomal protein L26 PRDX6 1q24.1 peroxiredoxin 6 MGC43026 1q24.2 hypothetical protein MGC43026 FLJ45235 1q24.2 FLJ45235 protein AB026190 1q24.1-q24.3 Kelch motif containing protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
multiple transmembrane segments
HOMOLOGY
interspecies ortholog to S.cerevisiae GPI2
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • glycosylphosphatidylinositol (GPI) anchor synthesis,class C
  • involved in transferring the third mannose of the GPI anchor,the first step of the synthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    glycosylation
    a component forming a complex with PIGH,PIGC and PIGQ in the endoplasmic membrane reticulum with GPI-GlcNac transferase activity
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS