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FLASH GENE
Symbol PIGC contributors: - updated : 03-01-2005
HGNC name phosphatidylinositol glycan, class C
HGNC id 8960
Location 1q23-q25      Physical location : 172.410.597 - 172.413.230
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     1 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
multiple transmembrane segments
HOMOLOGY
interspecies ortholog to S.cerevisiae GPI2
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • glycosylphosphatidylinositol (GPI) anchor synthesis,class C
  • involved in transferring the third mannose of the GPI anchor,the first step of the synthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    glycosylation
    a component forming a complex with PIGH,PIGC and PIGQ in the endoplasmic membrane reticulum with GPI-GlcNac transferase activity
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS