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FLASH GENE
Symbol PIGB contributors: - updated : 28-12-2006
HGNC name phosphatidylinositol glycan anchor biosynthesis, class B
HGNC id 8959
Location 15q21-q22      Physical location : 55.611.132 - 55.647.845
Synonym name phosphatidylinositol glycan, class B
Synonym symbol(s) MGC21236
EC.number 2.4.1.198
DNA
TYPE functioning gene
STRUCTURE 36.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
EEF1B1 15q15.1-q15.3 eukaryotic translation elongation factor 1 beta 1 ARPP-19 15q15.3 eukaryotic translation elongation factor 1 beta 1 FLJ10980 15q21.1 hypothetical protein FLJ10980 ONECUT1 15q21.1-q21.2 one cut domain, family member 1 LOC388122 15 similar to Laminin receptor 1 LOC390585 15 similar to Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu) LOC388123 15 LOC388123 FLJ38736 15q21.1 hypothetical protein FLJ38736 UNC13C 15q21.1 unc-13 homolog C (C. elegans) C15orf15 15q21 chromosome 15 open reading frame 15 RAB27A 15q15-q21.1 RAB27A, member RAS oncogene family PIGB 15q21-q22 phosphatidylinositol glycan, class B CPR8 15q21.1 phosphatidylinositol glycan, class B LOC145788 15q21.1 hypothetical LOC145788 DYX1C1 15q21 hypothetical LOC145788 PYGO1 15q21.1 pygopus 1 FLJ25756 15q21.1 hypothetical protein FLJ25756 NEDD4 15q15-q21.2 neural precursor cell expressed, developmentally down-regulated 4 FLJ12994 15q21.2 hypothetical protein FLJ12994 LOC390586 15 similar to L-3-hydroxyacyl-CoA dehydrogenase LOC161577 15q21.2 LOC161577 protein MNS1 15q21.2 meiosis-specific nuclear structural protein 1 FLJ20086 15q21.2 hypothetical protein FLJ20086 LOC145783 15q21.2 hypothetical protein LOC145783 TCF12 15q21 transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) LOC388124 15 LOC388124 FLJ14957 15q21.2 hypothetical protein FLJ14957 FLJ30973 15q21.2 hypothetical protein FLJ30973 GRINL1A 15q22.1 glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A ALDH1A2 15q21.2 aldehyde dehydrogenase 1 family, member A2 AQP9 15q22.1-q22.2 aquaporin 9 LOC145780 15q21.2 hypothetical LOC145780
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Lymphoid/Immunelymph node   highly
Urinarybladder   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticgranulocyte
cell lineage stem cell hematopoietic
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a glycosyltransferase motif
HOMOLOGY
Homologene
FAMILY dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • glycosyl-phosphatidylinositol (GPI) anchor synthesis,class B, involved in transferring the third mannose of the GPI anchor for cell surface proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS