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FLASH GENE
Symbol PI4K2B contributors: - updated : 04-07-2005
Location 4p15.2      Physical location : 25.235.652 - 25.280.831
Genatlas name phosphatidylinositol 4-kinase type-II beta
Synonym symbol(s) PI4KIIB, FLJ11105
DNA
TYPE functioning gene
STRUCTURE 45.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Respiratoryrespiratory tractlarynx  highly
Urinarybladder   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Pi4k2b
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
text peripheral membrane
basic FUNCTION
  • acting as a phosphotransferase with alcohol group as acceptor
  • stimulating phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by Rac-GTP
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS