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FLASH GENE
Symbol PHTF2 contributors: npt - updated : 03-02-2006
HGNC name putative homeodomain transcription factor 2
HGNC id 13411
Location 7q11.23-q21      Physical location : 77.428.108 - 77.586.818
Synonym symbol(s) DKFZp434D166, DKFZP564F013, FLJ33324, MGC86999
DNA
TYPE functioning gene
STRUCTURE 117.04 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
POR 7q11.2 P450 (cytochrome) oxidoreductase TMPIT 7q11.23 transmembrane protein induced by tumor necrosis factor alpha MK-STYX 7q11.23 map kinase phosphatase-like protein MK-STYX MDH2 7cen-q22 malate dehydrogenase 2, NAD (mitochondrial) LOC389525 7 similar to hypothetical protein LOC285908 LOC392060 7 similar to GrpE protein homolog 1, mitochondrial precursor (Mt-GrpE#1) (HMGE) LOC392061 7 similar to GTF2I repeat domain containing 1 isoform 2; Williams-Beuren syndrome chromosome region 11; GTF2I repeat domain-containing 1; general transcription factor 3; muscle TFII-I repeat domain-containing protein 1 alpha 1 FLJ37078 7q11.23 hypothetical protein FLJ37078 HSPB1 7q11.23 heat shock 27kDa protein 1 YWHAG 7q11.23 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide LOC392062 7 similar to peptidylprolyl isomerase A SRCRB4D 7p12.3 scavenger receptor cysteine rich domain containing, group B (4 domains) ZP3 7q11.23 zona pellucida glycoprotein 3 (sperm receptor) DTX2 7p12.3 deltex homolog 2 (Drosophila) UPK3B 7q11.2 uroplakin 3B POMZP3 7q11.23 POM (POM121 homolog, rat) and ZP3 fusion LOC392063 7 similar to Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) LOC370523 7q11.23 similar to deltex 2 LOC389526 7 hypothetical gene supported by AK024602 LOC389527 7 similar to PMS4 homolog mismatch repair protein - human LOC202802 7q11.23 similar to Williams Beuren syndrome chromosome region 19 FGL2 7q11.2 fibrinogen-like 2 LOC54103 7q21.11 hypothetical protein LOC54103 LOC392064 7 similar to hypothetical protein LOC392065 7 similar to beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; Glucosaminyl (N-acetyl) transferase 1, core 2; beta-1,6-N-acetylglucosaminyltransferase PTPN12 7q11.23 protein tyrosine phosphatase, non-receptor type 12 LOC389528 7 hypothetical gene supported by AF290475; BC037783 FLJ42526 7q21.11 FLJ42526 protein C7orf35 7q21.11 chromosome 7 open reading frame 35 PHTF2 7q11.23-q21 putative homeodomain transcription factor 2 AIP1 7q11.2 putative homeodomain transcription factor 2 LOC389529 7 LOC389529
RNA
TRANSCRIPTS type messenger
text variants 2 and 3 encode the same isoform
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 5025 - 751 - -
- - 5102 - 747 - -
- - 2548 - 356 - -
- - 2625 - 352 - -
- - 5013 - 747 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscular    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an atypical helix-turn-helix DNA binding domain
  • nine hydrophobic residues instead of twelve in the usual domain
  • a N terminal nuclear localization signal (NLS)
  • in the C terminal region, leucine residues that could form a leucine zipper and a beta-myc-type helix loop helix dimerization domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS