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FLASH GENE
Symbol PHF10 contributors: np/ - updated : 16-01-2007
HGNC name PHD finger protein 10
HGNC id 18250
Location 6q27      Physical location : 170.104.003 - 170.124.106
Synonym name
  • BRG1-associated factor, 45-KD, A
  • PHD zinc finger protein XAP135
  • Synonym symbol(s) FLJ10975, XAP135, MGC111009, BAF45a
    DNA
    TYPE functioning gene
    STRUCTURE 20.11 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    GPR31 6q27 G protein-coupled receptor 31 LOC389448 6 similar to T-complex protein 10A homolog LOC391986 6 similar to unc-93 homolog A UNC93A 6q27 unc-93 homolog A (C. elegans) C6orf104 LOC389449 6 LOC389449 TCP10 6q26 t-complex 10 (mouse) LOC391987 6 similar to Serine palmitoyltransferase 2 (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2) C6orf123 6q27 chromosome 6 open reading frame 123 MLLT4 6q27 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 LOC202546 6q27 hypothetical LOC202546 C6orf54 6q27 chromosome 6 open reading frame 54 KIF25 6q27 kinesin family member 25 FRMD1 6q27 FERM domain containing 1 LOC389450 6 LOC389450 LOC154323 6q27 hypothetical LOC154323 MGC33437 6q27 meningioma expressed antigen 6 (coiled-coil proline-rich) pseudogene DACT2 6q27 dapper homolog 2, antagonist of beta-catenin (xenopus) SMOC2 6q27 SPARC related modular calcium binding 2 LOC346055 6q27 similar to Hypothetical protein CBG10550 THBS2 6q27 thrombospondin 2 LOC391988 6 similar to SPCPB16A4.07c MGC43690 6q27 hypothetical protein MGC43690 PHF10 6q27 PHD finger protein 10 TCTE3 6q27 t-complex-associated-testis-expressed 3 C6orf208 6q27 chromosome 6 open reading frame 208 LOC154449 6q27 hypothetical protein LOC154449 DLL1 6q27 delta-like 1 (Drosophila) KIAA1838 6q27 KIAA1838 PSMB1 7p12 proteasome (prosome, macropain) subunit, beta type, 1 TBP 6q27 TATA box binding protein PDCD2 6q27 programmed cell death 2 LOC391989 6 similar to Olfactory receptor 4F3
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 1692 - 498 - 2002 11827455
    12 - 1686 - 496 - 2002 11827455
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineadrenal gland    
    Nervousbraindiencephalonhypothalamus  
     brainforebraincerebral cortex  
     gangliasensory gangliadorsal root  
    Reproductivefemale systemuterus   
     male systemprostate   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousneuron
    cell lineage
    cell lines gastric cancer cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two PHD zinc fingers
  • HOMOLOGY
    Homologene
    FAMILY
  • the REQUIEM/D4 family
  • SAYP family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may be having an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS