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FLASH GENE

Symbol

PHACTR3

contributors: - updated : 27-09-2006

HGNC name	phosphatase and actin regulator 3
HGNC id	15833

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	20q13.32-q13.33      Physical location : 58.179.602 - 58.422.764
Genatlas name	scaffold -associated protein phosphatase-1
Synonym name	scapinin
	chromosome 20 open reading frame 101
	scaffold-associated PP1 inhibiting protein
Synonym symbol(s)	H17739, C20orf101, SCAPIN1

DNA

TYPE	functioning gene
STRUCTURE	280.00 kb     16 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

text	four different leader exon (1A, 1B, 1C, 1D)

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed PHACTR3 V1 - - 2728 - 559 - Allen PHACTR3 V2 or SCAPININ L - - 2395 75 518 - Allen PHACTR3 V3 or SCAPININ S - - 2185 60 448 - Allen

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		fibrous
STRUCTURE

motifs/domains

HOMOLOGY

interspecies

ortholog to murine Phactr3

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytoskeleton,intermed filament
	intracellular,nucleus
text	associated with the chromatin-depleted nuclear structure
	attached to the nuclear matrix-intermediate filament (NM-IF)

basic FUNCTION	putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure
	playing an imporatant role in the brain

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS