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FLASH GENE
Symbol PGRMC2 contributors: npt - updated : 24-05-2005
HGNC name progesterone receptor membrane component 2
HGNC id 16089
Location 4q26      Physical location : 129.190.392 - 129.209.984
Synonym name
  • progesterone membrane binding protein
  • steroid receptor protein DG6
  • Synonym symbol(s) DG6, PMBP
    DNA
    TYPE functioning gene
    STRUCTURE 17.66 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 1873 23.8 223 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta, preferentially
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a putative transmembrane domain
  • a highly conserved stretch of 58AA
  • HOMOLOGY
    interspecies homolog to murine Pgrmc2
    homolog to rattus 25Dx
    homolog to Drosophilia Cg9066
    intraspecies homolog to PGRMC1
    Homologene
    FAMILY
  • cytochrome b5 family
  • MAPR subfamily
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • receptor for progesterone
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • steroid (like progesterone)
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS