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FLASH GENE
Symbol PGP contributors: mct - updated : 24-04-2012
HGNC name phosphoglycolate phosphatase
HGNC id 8909
Location 16p13.3      Physical location : 2.261.602 - 2.264.822
Synonym name
  • PGPase
  • Synonym symbol(s) MGC4692
    EC.number 3.1.3.18
    DNA
    TYPE functioning gene
    STRUCTURE 3.22 kb     2 Exon(s)
    MAPPING cloned Y linked Y status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 3136 - 321 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalyzes formation of phosphatidylglycerol from phosphatidylglycerophosphate
  • essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein PTPMT1 is a PGP phosphatase, having a role as a regulator of cardiolipin biosynthesis
    cell & other
    REGULATION
    Other PTPMT1 specifically dephosphorylates PGP
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS